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Familial Cluster of COVID-19 Infection from An Asymptomatic

Published time: 27 March 2020

Authors: Jinjun Zhang, Sijia Tian, Jing Lou, Yuguo Chen


Given that the asymptomatic persons are potential sources of COVID-19 infection, we report a familial cluster case of five patients infected with COVID-19 from an asymptomatic confirmed case in Beijing. We obtained the data of patients, which included demographic, epidemiological, and clinical features; chest radiography; laboratory test; and outcomes. Laboratory confirmation of COVID-19 was detected in the first hospital admission and verified by the Beijing Center for Disease Control and Prevention (CDC). An asymptomatic case was defined as a laboratory-confirmed COVID-19 infection case who was afebrile and well. We enrolled the family that had five patients in total with COVID-19 infection who were transferred by the Beijing Emergency Medical Service (EMS) from January 24 to 27, 2020, to the designated hospitals for special treatment. Clinical outcomes were followed up to February 29, 2020.

Familial cluster of COVID-19 infection from



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