Articles Virology Articles

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

Published time: 07 February 2020

Authors: Aiping Wu, Yousong Peng, Baoying Huang, Xiao Ding,  Xianyue Wang, Peihua Niu, Jing Meng, Zhaozhong Zhu, Zheng Zhang, Jiangyuan Wang,  Jie Sheng, Lijun Quan, Zanxian Xia, Wenjie Tan, Genhong Cheng, Taijiao Jiang

Keywords: Covid-19, SARS, pathogenic divergence


Abstract

An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused a functional and pathogenic divergence of 2019-nCoV.


Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

 

Reference: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(20)30072-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS193131282030072X%3Fshowall%3Dtrue

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