Published time: 06 April 2020
Authors: Manu Mitra
Keywords: Coronavirus, Ribonucleic acid, Protein, Antigen, Antibody, Vaccination Immunization, Middle East Respiratory Syndrome, Severe Acute Respiratory Syndrome
Coronavirus and its strains are associated to the subfamily of Orthocoronavirinae. It is associated with the family of Coronaviridae and the order of Nidovirales and the realm in Ribavirin. These are enveloped viruses with positive single stranded RNA genome and nucleocapsid of helical symmetry. The size of the genome for coronaviruses varies from 27 to 34 kilobases.
Mutation of Coronavirus may or may not be recognized by the immune system on subsequent infection; and once it highjacks host of the cell, replication of virus becomes faster. As a result immune system will be unable to recognize the strains of these infections; infections caused by coronavirus like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) have inclined to be very severe and can cause significant mortality. In this paper discusses about antigen and antibody for development of vaccines for coronavirus and its strains so that some of the B cells become memory B cells which recognize future exposure to the disease.
Antigen and antibody for Coronavirus RNA Vaccination Development