Published time: 06 May 2020
Authors: Nandini Sethuraman, Sundararaj Stanleyraj Jeremiah, Akihide Ryo
Keywords: Covid-19, diagnostic test, RT-PCR, immunosorbent.
The pandemic of coronavirus disease 2019 (COVID-19) continues to affect much of the world. Knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still evolving, and a clear understanding of the nature of the tests and interpretation of their findings is important. This Viewpoint describes how to interpret 2 types of diagnostic tests commonly in use for SARS-CoV-2 infections—reverse transcriptase–polymerase chain reaction (RT-PCR) and IgM and IgG enzyme-linked immunosorbent assay (ELISA)—and how the results may vary over time (Figure).
Interpreting Diagnostic Tests for SARS-CoV-2