Published time: 09 April 2020
Authors: Juanjuan Zhao, Xuejiao Liao, Haiyan Wang, Lanlan Wei, Mingzhao Xing, Lei Liu, Zheng Zhang
Keywords: SARS-CoV-2, COVID-19, HIV-1, HCV, Antibody
The effect of host immune status on SARS-CoV-2 infection remains unknown. Here, we report the first case of COVID-19 with HIV-1 and HCV co-infection, who showed a persistently negative SARS-CoV-2 RNA test, but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on the early SARS-CoV-2 clearance.
Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV