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Does the Direct Renin Inhibitor have a Role to Play in Attenuating Severity of the Outbreak Coronavirus Disease 2019 (COVID-19)?

Published time: 16 April 2020

Authors: Cheng-Wei Lin, Yu-Yao Huang

Keywords: Covid-19, public health


The ongoing outbreak of coronavirus disease 2019 (COVID-2019) was caused by the novel 2019 coronavirus (2019-nCoV), which shares a similar genome sequence with the SARS coronavirus (SARS-CoV).1,2 Like SARS-CoV, reports demonstrate that angiotensin-converting enzyme 2 (ACE2) could act as the receptor for 2019-nCoV.1,3 Moreover, studies have shown that 2019-nCoV binds ACE2 with a higher affinity than the original SARS virus strain.

Does the direct renin inhibitor have a role to play in attenuating severity of the outbreak coronavirus disease 2019 (COVID-19)



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